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Discussion The biotransformation of drugs usually leads to an increase of hydrophicility of a parent compound to support its excretion from the organism

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A Novel Mechanism Involved in the Enhancement of Glutathione Synthesis in Liver by Silymarin and Its Pharmacological Significance
Biomaterials 316:123024 Wu KK, Xu X, Wu M, Li X, Hoque M, Li GHY, Lian Q, Long K, Zhou T, Piao H, Xu A, Hui HX, Cheng KK (2024) MDM2 induces pro-inflammatory and glycolytic responses in M1 macrophages by integrating iNOS-nitric oxide and HIF-1 pathways in mice