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Ultrasmall porous silica nanoparticles (UPSN) were covered with DOTA, a chelator that binds the radionuclides 90 Y and 86Y for radiotherapy and PET imaging

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Successful transplantation in animal models has required immunosuppression, wherein chance of the graft rejection had been minimized using immunosuppressive therapy or genetically immune-deficient models (Cummings et al., 2005
