ipamorelin 2 mg TESAMORELIN/IPAMORELIN (8/2MG) CJC-1295 (Mod GRF 1-29) &

Oxidative stress is caused by an overproduction of superoxide and hydrogen peroxide or by a failure of the antioxidant system, ie glutathione and glutathione reductase

Curcumin is one of its main active ingredients, which can increase the survival rate of OHCs, reduce the expression of 4-HNE, and increase HO-1 expression, attenuates cisplatin-induced hearing loss [227], and studies have shown that curcumin attenuates all stages of head and neck squamous cell carcinoma progression (survival, proliferation), thus being an effective adjuvant to cisplatin and protecting against ototoxicity effect [228]

PMID: 10600876 Luppi F, Aarbiou J, van Wetering S, Rahman I, de Boer WI, Rabe KF, Hiemstra PS

Funding None declared