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Description
Treatment should not be delayed if neurological symptoms occur, as nerve damage may become irreversible without prompt B12 replacement

Downstream DAMP-associated microglia activation results in the assembly of the classical NADPH oxidase on the plasma membrane, resulting in the release of superoxides into the extracellular space, where they contribute to neuronal damage (Della Bianca et al., 1999)

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PMCID: PMC5295439
