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In cases of severe deficiency, a course of injections may be given over several weeks before transitioning to maintenance treatment

For chronic conditions, such as ongoing inflammation or gut issues, it may take a bit longertypically two to four weeksto see significant changes
, & Hampel, D

This selectivity represents a fundamental difference from not only full-length growth hormone but also growth hormone secretagogues and analogs like tesamorelin, which increase endogenous growth hormone and subsequently elevate IGF-1
