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Finally, the ROS-positive cell rate, the area proportion, and the fluorescence intensity of ROS-positive cells were observed and analyzed with a fluorescence microscope (Eclipse C1, Nikon, Tokyo, Japan)
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Chemotherapy with drugs like 5-fluorouracil has also been associated with acute thiamine deficiency by disrupting thiamine activation, so oncology patients receiving such therapy might receive parenteral thiamine supplementation as part of this B-Complex if needed
