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Moreover, the HIF1transfected RGs generated fewer earlyborn neurons that had already reached the cortical plate, but instead more recently born neurons that were still migrating through the IZ as compared to controls (Fig 5OP' and R), suggesting a delayed switch to differentiation by transient HIF1 overexpression

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Hormone Optimization If adrenal dysfunction is impacting sex hormones or thyroid, bioidentical hormone replacement may be considered