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For example, the TfR1 inhibitor Ferstatin II significantly suppresses TfR1 activity in vitro and in vivo , improving cartilage degradation
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[DOI] [PMC free article] [PubMed] [Google Scholar] Mamelak M
This bidirectional gene modulation profile simultaneously promoting tissue remodeling while suppressing destructive inflammation is unusually broad for a tripeptide and distinguishes GHK-Cu from most single-target peptide ligands in the research literature
