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This indicates that alterations in intestinal epithelium integrity caused by genetic or environmental factors contributes to the translocation of luminal microbes that can become immunogenic when delocalised from their GI niche (Fine et al

The daily dose should be 3060 mg [62]

Importantly, dysbiosis can also lead to disruption of epithelial barrier leading to unwanted consequences [50] (Figure 2)

Individual dosing should be personalized based on body weight, baseline body composition, metabolic status, response to therapy, and physician assessment
