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Mitochondria-derived methylmalonic acid aggravates ischemia-reperfusion injury by activating reactive oxygen species-dependent ferroptosis

Autophagy is regulated by two main pathways that overlap with IGF-1 signaling pathways: mTOR-mediated inhibitory phosphorylation of unc51-like kinase-1 (ULK1) and FoxO3-mediated induction of autophagy-related genes

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