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Revised Date: January 18, 2023 Recommendations and Topics Scope Key Recommendations Background Epidemiology Patient Risk Factors Associated with B 12 Deficiency Patient Risk Factors Associated with Folate Deficiency Prevention Diagnosis Management Ongoing Care References Resources Appendix A: Dietary sources of cobalamin Scope This guideline covers the primary care investigation and management of cobalamin (vitamin B 12 or simply B 12 ) and folate deficiency in adults

Treatment must be started promptly following diagnosis to reduce the risk of irreversible neurological symptoms (see Table 2)[17]

6 (1), e139826

[PubMed] [Google Scholar] 133.Pajardi G., Bortot P., Ponti V., Novelli C