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Autoimmune diseases commonly linked to peripheral neuropathy include: Sjogrens syndrome Systemic lupus erythematosus (SLE) Rheumatoid arthritis (RA) Psoriasis/psoriatic arthritis Guillain-Barre syndrome Type 1 diabetes Classified as a metabolic disorder rather than an autoimmune disease, Type 2 diabetes is the most common underlying cause of peripheral neuropathy

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Consistent with these studies, a recent study in healthy NS workers demonstrated that moderate alcohol consumption further altered peripheral clock gene amplitude in CLOCK, BMAL1, PER1, CRY1, and CRY2, and it was associated with increased colonic permeability, highlighting the compounding effects of environmental circadian disruption and lifestyle factors on peripheral clock gene regulation 143
