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Description
They chose to mainly target DUX4 exon 3, which is specifically associated with the pathogenic DUX4 transcript (see DUX4 gene expression)
There is no good evidence supporting phlebotomy treatment for individuals with unexplained elevated ferritin levels caused by other conditions, such as fatty liver disease, or where iron overload has not been definitively proven by confirmatory testing as described above (Quantification of Liver Iron)
Phytochem Rev 21:537
GPR109A and vascular inflammation
