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See 2026 research, FDA warnings, side effects, and why experts advise caution before treatment.

If it remains persistent or occurs in other etiologies, immunomodulatory treatments may be needed

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However, a growing body of evidence now unequivocally demonstrates that smoking negatively influences the incidence, severity, and outcomes of a wide spectrum of hepatic conditions, including metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol-related liver disease (ALD), chronic viral hepatitis (HBV and HCV), primary biliary cholangitis (PBC), and hepatocellular carcinoma (HCC)