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Interrupting the blood supply causes several pathophysiological alterations that lead to irreversible neural disruption, such as the production of oxygen free radicals and cerebral edema, reactive oxygen species, neuroinflammation, blood-brain barrier (BBB) destruction, and local inflammatory cell infiltration (Wang et al., 2021)
Liver function tests (AST, ALT) and lipid panels help assess hepatic status and choline demand

42 KolbH
examined the effects of cell passage, sample processing batch, and instrumental batch drifting on metabolomic profiles of a series of identical samples, to examine how these factors interact (Moreno-Torres et al., 2021)