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At 0.5mm, a stamped microneedle traverses the stratum corneum (typically 10 to 30 microns), passes through the viable epidermis (50 to 100 microns), and lands in the upper papillary dermis (which begins around 100 to 150 microns deep)
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Immunoblots were quantified using ImageJ, and values were divided by actin or total H3 histones normalized to the control treatment values
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