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Description
It has been reported that this microbiome has a diverse role as it maintains a dynamic and regulated interaction with the immune system, which, upon shifting microbiome patterns, plays a key role in rejection in recipients of organ transplants by dysregulating the immune system

Not only could this involve mitigating LN-induced tissue damage by inhibiting the differentiation and survival of Teff cells, but it could also enhance immune tolerance by increasing the number of Treg cells, allowing for a more targeted approach to treating LN

CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease

Dorr RT, Peng YM, Alberts DS
