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Description
Melanocortins (MCs) are multifunctional peptide hormones that regulate a diversity of physiological functions
The chemotherapeutic agent methotrexate (MTX) causes an increase in MITF and its direct target TYR (tyrosinase) that inhibit invasiveness in melanoma
The dermatofibrosarcoma protuberans, especially the Bednar tumor or pigmented variant, can sometimes be confused with a fibroblastic variant of the congenital nevus
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