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Interestingly with Chen et al, it was noted that those reported improvement had low urinary nitrite/nitrate, the excreted metabolic products of NO, suggesting that those with low NO levels are more likely to improve with L-arginine supplementation

If you start noticing irritation, redness, or other side effects, stop using it

Recent progress in pharmacological research of propolis

doi: 10.1016/j.cmet.2014.06.015
