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Common side effects can include gastrointestinal discomfort (bloating, cramping, diarrhea), headaches, and allergic reactions in some individuals

Ethics statement The animal study was reviewed and approved by Shanghai University of Traditional Chinese Medicine Animal Experiment Ethics Committee

used C57BL/6 mice as the animal model to induce oxidative stress using paraquat (McCormack et al., 2005)

Cancer Res 43:49014905 Feinberg AP, Gehrke CW, Kuo KC, Ehrlich M (1988) Reduced genomic 5-methylcytosine content in human colonic neoplasia
