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doi: 10.1016/j.dsx.2017.12.016 69 ParkerB
This affects the upstream metabolites in the methionine and transsulfuration pathways because GSSG inhibits the enzymes MAT-I and MAT-III [57, 58]
CARS2 mutant lacking the persulfide synthesis activity did not rescue the decreased mitochondrial membrane potential of CASR2-deficient cells, whereas CARS2 mutant lacking cysteinyl t-RNA synthesis activity did
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