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Thus, the anti-aging insulin/IGF-signaling pathway mediated by DAF-16 is likely to be inhibited by NAC

Kurashima-Ito K, Kasai Y, Hosono K, Tamura K, Oue S, Isogai M, Ito Y, Nakamura H, Shiro Y (2005) Solution structure of the C-terminal transcriptional activator domain of FixJ from Sinorhizobium meliloti and its recognition of the fixK promoter

Furthermore, it has been observed that hyperhomocysteinemia is often associated with endothelial dysfunction and inflammation, both of which are known to contribute to the development and progression of diabetic retinopathy

doi: 10.1074/jbc.M116.748129
