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Green et al 26 Severe clinical abnormalities should be treated intensively with B 12 , cyanoB 12 or hydroxyB 12 : HydroxyB 12 is commonly used in Europe, often at intervals of 23 months, as it seems to have better retention than cyanoB 12
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In the clinic, he described several months of waxing and waning nodular lesions on the left upper extremity with intermittent spontaneous drainage (Fig
