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It was demonstrated that curcumin nano-formulations exhibited excellent solubility and stability, along with antioxidant and enzyme inhibition properties, as evidenced by molecular docking and simulation studies ( FIGURE 1 In light of the increasing interest in natural medicine for the management of NDs, curcumin has garnered extensive attention as a highly promising therapeutic agent

doi: 10.1016/j.cell.2025.02.009 Summary Keywords antiretroviral therapy, cGAS-STING, HIV, immunometabolism, inflammaging, mtDNA, oxidative stress Citation Ma L, Wang X and Xu H (2026) Mitochondrial DNA damage in HIV infection: a mechanistic driver of immunometabolic dysfunction and chronic inflammation

Effective activation of these receptors may have significant therapeutic benefits and prospects in anti-cancer immunity [111,112,113,114]

The lowest concentration of HCH and BSO for the synergistic effect was 5 M and 25 M respectively