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The findings of this meta-analysis demonstrated that silymarin at a dose of less than 400 mg showed greater decreasing effects on AST and ALT levels compared to its high doses

Adenovirus, a double-stranded DNA virus, is a commonly utilized viral vector for SARS-CoV-2 vaccine development [181, 182], but limited research utilized adenoviruses for mRNA delivery

However, activating NRF2 may increase the risk of cancer in the elderly, as NRF2 activation protects cancer cells from oxidative damage, which contributes to the progression of cancer [177, 178]

Specific allergic manifestations consisting of swelling of eyelids, lips, pharynx and larynx, urticaria, asthma, and bronchospasm, sometimes with a concomitant fall in blood pressure