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Our mRNALNP vaccine formulations utilized different phospholipids and varying ratios of polyethylene glycol lipid, whereas the ionizable lipid and cholesterol remained approximately constant

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This finding is in broad agreement with previously determined apo and moenomycin-bound structures of Ec PBP1b that show that antibiotic binding is accompanied by a rigid-body tilting of TP and UB2H domains towards the GT domain 40,41,42 (SI Fig

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