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In T2D, FA spillover from adipocytes increases hepatic acetyl-CoA, an allosteric regulator of pyruvate carboxylase activity, resulting in greater gluconeogenesis in the liver (183, 200)

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[19] have suggested that based on consensus of the literature, the GH Research Society Consensus (RSC) from Port Stevens in 1997 [18] and its Consensus Statements should be appropriately amended