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Nothing herein should be interpreted as medical claims, treatment recommendations, or diagnostic guidance

doi: 10.1126/science.1523409

partial sequence of human Body Protection Compound Sequence: H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH (GEPPPGKPADDAGLV) CAS Number: 137525-51-0 Molecular Formula: C 62 H 98 N 16 O 22 Molecular Weight: 1419.55 g/mol Mechanism (working): modulation of nitric oxide system, VEGFR-2 expression, and growth factor signaling supporting GI, vascular, and connective-tissue repair Regulatory status: not approved by the FDA or EMA TB-500 Compound class: synthetic N-acetylated heptapeptide

We found no difference in concentration of ES2 resulting in cell death when comparing doxorubicin to these pro-senescence agents suggesting that ES2 works robustly on senescent cells regardless of senescence inducer
