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doi: 10.1186/s12990-015-0009-2 [DOI] [PMC free article] [PubMed] [Google Scholar] 77.Khalefa HG, Shawki MA, Aboelhassan R, et al

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The oncogenic role of ferroptosis While ferroptosis is primarily known for its tumor-suppressive function, it can also paradoxically promote tumor progression through its effects on immune cells and the TME

This effect is primarily attributed to the substantial leakage of reactive oxygen species (ROS) resulting from the disruption of the electron transport chain [52, 53]