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Six years after discontinuation, the level became low again, and she is now receiving regular intramuscular injections

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According to a recent literature review that included seven clinical trials assessing the efficacy of vitamin B12 supplementation in patients with T2D receiving metformin treatment, daily supplementation with methylcobalamin through oral or sublingual administration is preferred over the intramuscular route, considering its effectiveness, cost, and convenience for patients [57]

[DOI] [PubMed] [Google Scholar] 47.Pagn K., Hou J., Goldenberg R
