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By synthesizing current research advancements, the present review aims to provide new perspectives on the common pathological pathways underlying these diseases and to establish a theoretical foundation to guide the development of effective clinical interventions

However, although disease control rates were relatively high and responses were reported to be durable, studies were limited by a small subgroup size

Neurotoxins (or neuromodulators), such as Botox, work by temporarily relaxing specific facial muscles to soften dynamic lines that form with expression