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10.3748/wjg.v20.i44.16639 World J

This is especially important for biologics that can cross the blood-brain barrier to effectively control inflammatory injury and mitigate the corresponding deleterious effects on the brain and peripheral tissues

With regard to the increased secretion of EVs during the progression of NAFLD, experimental studies demonstrated that toxic lipids significantly increase the production of hepatocyte-derived EVs, which act as mediators of paracrine signaling, causing hepatic stellate cell activation, angiogenesis and activation of macrophages leading to inflammation and chemotaxis [103,104,105]

August 15 Product : AstraZenecas Imfinzi Indication : Perioperative non-small cell lung cancer AstraZeneca won a new indication for Imfinzi on Thursday when the FDA green lit the drug, along with platinum-containing chemotherapy, for the perioperative treatment of non-small cell lung cancer (NSCLC)