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That said, mild effects can occur in some people, especially when starting any new supplement: Temporary bloating or fullness (more common with collagen) Mild digestive discomfort if taken without enough water These are usually short-lived and can be reduced by: Taking supplements with adequate water Starting with recommended doses Choosing high-quality, well-absorbed formulations Using clinically formulated products from trusted brands helps minimize unnecessary reactions

Fatigue persists after four weeks: Levels may still be suboptimal

[31] but contradicts Thomas et al.s finding that increased LPCs and SM corresponded to more favorable outcomes at 6 months [31]

Kang GG, Francis N, Hill R, Waters D, Blanchard C, Santhakumar AB (2019) Dietary polyphenols and gene expression in molecular pathways associated with type 2 diabetes mellitus: a review