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Curcumin-treated cells showed elevated ROS, MDA and Fe2+ levels, decreased SOD, GSH and GPX4 levels, and increased nuclear NRF2 level and nuclear translocation, and HMOX1 expression, suggesting that curcumin activated the NRF2/HMOX1 pathway to promote ferroptosis, thereby inhibiting lung cancer cell malignant progression

Nevertheless, despite these encouraging findings, existing research on the specific pathways by which gut microbiota modulate the ENS to ameliorate GI issues in patients with diabetes remains insufficient

The B -factors of the crystal structures were calculated by Baverage 53 , and the volumes of the protein cavities were calculated using the CASTp server 54 with a probe radius of 1.4

pro Portion (10 ml)