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Bernal et al

4.5.4 Possible side effects and potential health risks While spermidine offers therapeutic benefits, its use in treating ocular conditions must be approached with caution due to potential cytotoxic effects

Androgen stimulates glycolysis for de novo lipid synthesis by increasing the activities of hexokinase 2 and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 in prostate cancer cells