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[136] [137] [138] As an ESPN writer described it: "He'll swing his hips or spread his legs or sweep his feet or shimmy his shoulders or lick his lips or squeeze his, um, junk, sometimes all at once." [137] Soto says he started the routine in the minor leagues "to get in the minds of the pitchers, because sometimes they get scared"

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It was proposed that this accommodation allows enzalutamide to directly contact F876, resulting in a conformational rearrangement in helix 11 that prevents helix 12 from adopting the agonist conformation required for coactivator binding