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10.1038/s41580-020-0236-x 163 VieiraS
Results NO drives PDHC and OGDC inhibition by altering lipoic arm We recently discovered that stimulation of macrophages by LPS + IFN- led to a profound inhibition of PDHC and OGDC over time 11
From the onset of biological development, intracellular reactive oxygen species (ROS) homeostasis is self-regulated to ensure the maintenance of ROS levels and a dynamic equilibrium within cells and tissues [2, 3]
233 Upon escalating the dose to 0.17 mg m 2 day 1 , severe myelosuppression and gastro-intestinal toxicity were observed
