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Much of the fear of a Herxheimer reaction comes not from the symptoms, but from the fear of losing control

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& Mott, D

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Capillary supports have been used with affinity ligands since the early 1980s and, as shown in Figure 4, represent the second most popular format over the last 50 years [76,77]

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However, during the treatment of neonatal hyperbilirubinemia, the level of free bilirubin in the serum is decreased, which may weaken the protective effect of bilirubin on the cell membrane, thus making the cell membrane susceptible to injury and causing cell apoptosis

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