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Many other lactones have antitumor activities, including alantolactone which shows almost similar activities against many tumors as ISA (Liu X

302 In addition, H 2 O 2 directly activates AMPK in HEK-293 cells by oxidatively modifying Cys299 and Cys304 of the AMPK subunit 303 (Table 1, Fig

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Footnotes Appendix A Supplementary data to this article can be found online at Contributor Information Chunfeng Yao, Email: [email protected]