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GPx3 dysregulation impacts adipose tissue insulin receptor expression and sensitivity

488 In the clinic, cognitive tests and patient/carer history remain the mainstay methods for identifying AD signs and symptoms (amnesia, disorientation, mood changes, etc.), and additional laboratory tests (full blood count, metabolic panel, etc.) are used to rule out differential diagnoses (e.g., metabolic causes of dementia), often with radiological imaging (MRI/PET) to assess neurodegeneration and rule out vascular dementia

suggests that the perioperative administration of an appropriate dose of dexmedetomidine can reduce the release of inflammatory mediators and neuroendocrine hormones, maintain cerebral homeostasis, and alleviate ischemic brain injury, thereby exerting a protective effect on the brain [44]

doi: 10.7759/cureus.50534 [DOI] [PMC free article] [PubMed] [Google Scholar] 5.Lenti MV, Rugge M, Lahner E, et al