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Age and altered kidney function variables are the main drivers of circulating TMAO in BMIS To better understand which variables (Supplemental Data 1) affect circulating TMAO most, we trained extreme gradient-boosted decision-tree models
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For comparison, in a cross-sectional study in the UK Biobank, 168 metabolites were measured in plasma samples from 2,238 prevalent glaucoma cases and 44,723 controls using NMR spectroscopy (Nightingale, Finland
