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Hypoxic conditions are known to elevate the rate of glycolysis, and thus methylglyoxal production is expected to be elevated when oxygen is low
Chem Soc Rev

Amino Acids 45:479488 Ren WK, Liu SP, Chen S et al (2013b) Dietary L-glutamine supplementation increases pasteurella multocida burden and expression of major virulence factors

A possible molecular NK between Parkinsons disease and heavy metal exposure