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In aggregate, CSP-induced derangement in LC was attributed to a combination of cytotoxicity that caused a release of LC from damaged tissues, and impaired renal reabsorption mechanisms, as well as inhibition of the cellular uptake of LC caused by a change in OCTN2 activity

After being acidified, the above solution was extracted with ethyl ether to produce (R)-3,4-epoxybutyric acid with a yield of 55%
