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l glutathione oxidised L-Glutathione (GSSG) | CAS 27025-41-8 GSSG plays an essential role in cellular redox balance Chemical structures of glutathione (GSH)
Description
Small molecule inhibitors such as RSL3 and ML162 mediate alkylation on GPX4 by binding to the selenium cysteine 46 residue by electrophilic alkyl chloride moieties (Eaton et al., 2020
& Hammes, F

However, concerns remain regarding potential harm to humans from specific compounds that have shown hazardous effects in laboratory animals

Lancet 382, 597604
