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Description
Significant improvement in the symptom score and flow rate was observed with 1 -AR antagonists alone or combination therapy as compared to placebo or finasteride alone, but there was no significant difference observed for combination therapy over 1 -AR antagonists alone
Dimeric SP1 can bind to GC-rich sequences of GGGCGG, but the binding affinity and transcription properties vary according to the interacting cofactors [1719]
The appetite regulation influences represent another significant advantage of this dual-agonist mechanism
Journal of Mammalogy, 97 , 663688
