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[DOI] [Google Scholar] Tang S
In contrast, an increase in extracellular Ca 2+ concentration increases the probability of Na + channel closure and results in decreased excitability of peripheral neurons (Armstrong and Cota, 2+ /Mg 2+ prior to oxaliplatin infusion has been evaluated in several clinical trials as a strategy to prevent development of CIPN, although a consistent clinical benefit is unfortunately not apparent (Jordan et al., 2016)
