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Similar content being viewed by others Introduction Dimethyl sulfoxide (DMSO) is the most commonly used nonaqueous solvent and is classified as class 3 (nontoxic) by the United States Food and Drug Administration (FDA) and the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) 1,2

Note that these doses are specific to cyanocobalamin, the preferred supplemental form of vitamin B12, as there is insufficient evidence to support the efficacy of the other forms, like methylcobalamin

B12 is a key player in the production of the mood-regulating chemical serotonin and when your body is lacking the vitamin, production can decrease