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A landmark 1989 RCT of 170 patients with cirrhosis (many with alcoholic etiology) found that 420 mg silymarin daily for a mean of 41 months significantly reduced overall mortality compared to placebo, with a more pronounced effect in the alcoholic cirrhosis subgroup, reporting a 58% four-year survival rate versus 39% in placebo (Ferenci, 1989) [32]
Natural product pectolinarigenin exhibits potent anti-metastatic activity in colorectal carcinoma cells in vitro and in vivo
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[DOI] [PubMed] [Google Scholar] [236].Katsuyama M, Kimura E, Ibi M, et al
