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10.1210/en.2018-00750 115

Targeting p53 presents a substantial risk of off-target effects

The controls that underlie the hair cycle reside within the hair follicle itself, and are believed to result from changes in the intra- and perifollicular expression of specific regulatory molecules and their receptors [8, 9]

The interaction energy at the protein-protein interface of the investigated mutants C484A and C484W was also calculated by using the same FoldX AnalyseComplex assay