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The primary treatment option for persistent plaque psoriasis, particularly if psoriasis arthritis has been manifested, is methotrexate [21]
[DOI] [PubMed] [Google Scholar] Chien SJ, Lin IC, Hsu CN, Lo MH, Tain YL
[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Starke IC, Pieper R, Neumann K, Zentek J, Vahjen W
Unlocking melatonins potential: evidence from observational studies and trials The use of melatonin in older adults is increasing over time
